Generation of both cortical and Aire(+) medullary thymic epithelial compartments from CD205(+) progenitors

In the adult thymus, the development of self-tolerant thymocytes requires interactions with thymic epithelial cells (TECs). Although both cortical and medullary TECs (cTECs/mTECs) are known to arise from common bipotent TEC progenitors, the phenotype of these progenitors and the timing of the emerge...

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Huvudupphovsmän: Baik, Song, Jenkinson, Eric J, Lane, Peter J L, Anderson, Graham, Jenkinson, William E
Materialtyp: Artigo
Språk:Inglês
Publicerad: BlackWell Publishing Ltd 2013
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960635/
https://ncbi.nlm.nih.gov/pubmed/23299414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201243209
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