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Generation of both cortical and Aire(+) medullary thymic epithelial compartments from CD205(+) progenitors
In the adult thymus, the development of self-tolerant thymocytes requires interactions with thymic epithelial cells (TECs). Although both cortical and medullary TECs (cTECs/mTECs) are known to arise from common bipotent TEC progenitors, the phenotype of these progenitors and the timing of the emerge...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BlackWell Publishing Ltd
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3960635/ https://ncbi.nlm.nih.gov/pubmed/23299414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201243209 |
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