Loading...

Alterations of the medullary epithelial compartment in the Aire-deficient thymus: Implications for programs of thymic epithelial differentiation

A widely held model of thymic epithelial differentiation is based on patterns of keratin expression, where a K8(+)K5(+) progenitor gives rise to K8(+)K5/K14(−) cortical thymic epithelium (CTEC), and medullary thymic epithelium (MTEC) is K8(−)K5(+)K14(+). The thymic phenotype of p63-deficient mice in...

Full description

Saved in:
Bibliographic Details
Main Authors: Dooley, James, Erickson, Matthew, Farr, Andrew G.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677919/
https://ncbi.nlm.nih.gov/pubmed/18832676
Tags: Add Tag
No Tags, Be the first to tag this record!