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Alterations of the medullary epithelial compartment in the Aire-deficient thymus: Implications for programs of thymic epithelial differentiation

A widely held model of thymic epithelial differentiation is based on patterns of keratin expression, where a K8(+)K5(+) progenitor gives rise to K8(+)K5/K14(−) cortical thymic epithelium (CTEC), and medullary thymic epithelium (MTEC) is K8(−)K5(+)K14(+). The thymic phenotype of p63-deficient mice in...

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Autors principals: Dooley, James, Erickson, Matthew, Farr, Andrew G.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677919/
https://ncbi.nlm.nih.gov/pubmed/18832676
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