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Alterations of the medullary epithelial compartment in the Aire-deficient thymus: Implications for programs of thymic epithelial differentiation
A widely held model of thymic epithelial differentiation is based on patterns of keratin expression, where a K8(+)K5(+) progenitor gives rise to K8(+)K5/K14(−) cortical thymic epithelium (CTEC), and medullary thymic epithelium (MTEC) is K8(−)K5(+)K14(+). The thymic phenotype of p63-deficient mice in...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2677919/ https://ncbi.nlm.nih.gov/pubmed/18832676 |
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