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DNA methylation profile of Aire-deficient mouse medullary thymic epithelial cells

BACKGROUND: Medullary thymic epithelial cells (mTECs) are characterized by ectopic expression of self-antigens during the establishment of central tolerance. The autoimmune regulator (Aire), which is specifically expressed in mTECs, is responsible for the expression of a large repertoire of tissue-r...

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Bibliografiske detaljer
Main Authors: Wu, Guoying, Hirabayashi, Keiji, Sato, Shinya, Akiyama, Nobuko, Akiyama, Taishin, Shiota, Kunio, Yagi, Shintaro
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3546423/
https://ncbi.nlm.nih.gov/pubmed/23116172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-13-58
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