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DNA methylation profile of Aire-deficient mouse medullary thymic epithelial cells
BACKGROUND: Medullary thymic epithelial cells (mTECs) are characterized by ectopic expression of self-antigens during the establishment of central tolerance. The autoimmune regulator (Aire), which is specifically expressed in mTECs, is responsible for the expression of a large repertoire of tissue-r...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3546423/ https://ncbi.nlm.nih.gov/pubmed/23116172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-13-58 |
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