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TNF receptor family signaling in the development and functions of medullary thymic epithelial cells

Thymic epithelial cells (TECs) provide the microenvironment required for the development of T cells in the thymus. A unique property of medullary thymic epithelial cells (mTECs) is their expression of a wide range of tissue-restricted self-antigens, critically regulated by the nuclear protein AIRE,...

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Detalhes bibliográficos
Main Authors: Akiyama, Taishin, Shinzawa, Miho, Akiyama, Nobuko
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432834/
https://ncbi.nlm.nih.gov/pubmed/22969770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00278
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