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TNF receptor family signaling in the development and functions of medullary thymic epithelial cells
Thymic epithelial cells (TECs) provide the microenvironment required for the development of T cells in the thymus. A unique property of medullary thymic epithelial cells (mTECs) is their expression of a wide range of tissue-restricted self-antigens, critically regulated by the nuclear protein AIRE,...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Frontiers Media S.A.
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3432834/ https://ncbi.nlm.nih.gov/pubmed/22969770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00278 |
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