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Thymic nurse cells provide microenvironment for secondary T cell receptor α rearrangement in cortical thymocytes

Distinct subsets of thymic epithelial cells (TECs) support T-cell development and selection. Isolated TECs contain multicellular complexes that enclose many viable thymocytes. However, the functions of those TECs, termed thymic nurse cells (TNCs), are unclear and the idea that TNCs are present in vi...

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Main Authors: Nakagawa, Yasushi, Ohigashi, Izumi, Nitta, Takeshi, Sakata, Mie, Tanaka, Keiji, Murata, Shigeo, Kanagawa, Osami, Takahama, Yousuke
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528577/
https://ncbi.nlm.nih.gov/pubmed/23188800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1213069109
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