Foxn1-β5t transcriptional axis controls CD8(+) T-cell production in the thymus

The thymus is an organ that produces functionally competent T cells that protect us from pathogens and malignancies. Foxn1 is a transcription factor that is essential for thymus organogenesis; however, the direct target for Foxn1 to actuate thymic T-cell production is unknown. Here we show that a Fo...

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Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Uddin, Muhammad Myn, Ohigashi, Izumi, Motosugi, Ryo, Nakayama, Tomomi, Sakata, Mie, Hamazaki, Jun, Nishito, Yasumasa, Rode, Immanuel, Tanaka, Keiji, Takemoto, Tatsuya, Murata, Shigeo, Takahama, Yousuke
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2017
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5309848/
https://ncbi.nlm.nih.gov/pubmed/28176764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14419
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