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Thymus machinery for T-cell selection

An immunocompetent and self-tolerant pool of naive T cells is formed in the thymus through the process of repertoire selection. T cells that are potentially capable of responding to foreign antigens are positively selected in the thymic cortex and are further selected in the thymic medulla to help p...

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Detalles Bibliográficos
Publicado en:Int Immunol
Main Authors: Kondo, Kenta, Ohigashi, Izumi, Takahama, Yousuke
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6400048/
https://ncbi.nlm.nih.gov/pubmed/30476234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxy081
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