Comprehensively Profiling the Chromatin Architecture of Tissue Restricted Antigen Expression in Thymic Epithelial Cells Over Development

Thymic epithelial cells (TEC) effect crucial roles in thymopoiesis including the control of negative thymocyte selection. This process depends on their capacity to express promiscuously genes encoding tissue-restricted antigens. This competence is accomplished in medullary TEC (mTEC) in part by the...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Handel, Adam E., Shikama-Dorn, Noriko, Zhanybekova, Saule, Maio, Stefano, Graedel, Annina N., Zuklys, Saulius, Ponting, Chris P., Holländer, Georg A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156148/
https://ncbi.nlm.nih.gov/pubmed/30283453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02120
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