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Biologically indeterminate yet ordered promiscuous gene expression in single medullary thymic epithelial cells
To induce central T‐cell tolerance, medullary thymic epithelial cells (mTEC) collectively express most protein‐coding genes, thereby presenting an extensive library of tissue‐restricted antigens (TRAs). To resolve mTEC diversity and whether promiscuous gene expression (PGE) is stochastic or coordina...
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| Publicado no: | EMBO J |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6939203/ https://ncbi.nlm.nih.gov/pubmed/31657037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019101828 |
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