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Promiscuous gene expression patterns in single medullary thymic epithelial cells argue for a stochastic mechanism
Promiscuous expression of tissue-restricted autoantigens in medullary thymic epithelial cells (mTECs) imposes central T cell tolerance. The molecular regulation of this unusual gene expression is not understood, in particular its delineation from cell lineage-specific gene expression control remains...
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| Asıl Yazarlar: | , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
National Academy of Sciences
2008
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2206592/ https://ncbi.nlm.nih.gov/pubmed/18180458 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707486105 |
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