Загрузка...

Promiscuous gene expression patterns in single medullary thymic epithelial cells argue for a stochastic mechanism

Promiscuous expression of tissue-restricted autoantigens in medullary thymic epithelial cells (mTECs) imposes central T cell tolerance. The molecular regulation of this unusual gene expression is not understood, in particular its delineation from cell lineage-specific gene expression control remains...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Derbinski, Jens, Pinto, Sheena, Rösch, Stefanie, Hexel, Klaus, Kyewski, Bruno
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2008
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2206592/
https://ncbi.nlm.nih.gov/pubmed/18180458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707486105
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!