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Genome-wide gene expression profiling of homeodomain-interacting protein kinase 2 deficient medullary thymic epithelial cells

The establishment of central tolerance essentially depends on the promiscuous gene expression (pGE) of a plethora of tissue restricted antigens by the medullary thymic epithelial cells. The antigens are presented to developing thymocytes in the thymus to select for non-self reactive T-cell receptors...

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Pubblicato in:Genom Data
Autori principali: Rattay, Kristin, Derbinski, Jens, Hofmann, Thomas G., Kyewski, Bruno
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4664679/
https://ncbi.nlm.nih.gov/pubmed/26697330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gdata.2015.08.004
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