Dynamic spatio‐temporal contribution of single β5t+ cortical epithelial precursors to the thymus medulla

Intrathymic T‐cell development is critically dependent on cortical and medullary thymic epithelial cells (TECs). Both epithelial subsets originate during early thymus organogenesis from progenitor cells that express the thymoproteasome subunit β5t, a typical feature of cortical TECs. Using in vivo l...

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Detalhes bibliográficos
Publicado no:Eur J Immunol
Main Authors: Mayer, Carlos E., Žuklys, Saulius, Zhanybekova, Saule, Ohigashi, Izumi, Teh, Hong‐Ying, Sansom, Stephen N., Shikama‐Dorn, Noriko, Hafen, Katrin, Macaulay, Iain C., Deadman, Mary E., Ponting, Chris P., Takahama, Yousuke, Holländer, Georg A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Cellular Immune Response
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832341/
https://ncbi.nlm.nih.gov/pubmed/26694097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201545995
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