Dynamic spatio‐temporal contribution of single β5t+ cortical epithelial precursors to the thymus medulla

Intrathymic T‐cell development is critically dependent on cortical and medullary thymic epithelial cells (TECs). Both epithelial subsets originate during early thymus organogenesis from progenitor cells that express the thymoproteasome subunit β5t, a typical feature of cortical TECs. Using in vivo l...

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Bibliografske podrobnosti
izdano v:Eur J Immunol
Main Authors: Mayer, Carlos E., Žuklys, Saulius, Zhanybekova, Saule, Ohigashi, Izumi, Teh, Hong‐Ying, Sansom, Stephen N., Shikama‐Dorn, Noriko, Hafen, Katrin, Macaulay, Iain C., Deadman, Mary E., Ponting, Chris P., Takahama, Yousuke, Holländer, Georg A.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2016
Teme:
Cellular Immune Response
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832341/
https://ncbi.nlm.nih.gov/pubmed/26694097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201545995
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