Dynamic spatio‐temporal contribution of single β5t+ cortical epithelial precursors to the thymus medulla

Intrathymic T‐cell development is critically dependent on cortical and medullary thymic epithelial cells (TECs). Both epithelial subsets originate during early thymus organogenesis from progenitor cells that express the thymoproteasome subunit β5t, a typical feature of cortical TECs. Using in vivo l...

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Vydáno v:Eur J Immunol
Hlavní autoři: Mayer, Carlos E., Žuklys, Saulius, Zhanybekova, Saule, Ohigashi, Izumi, Teh, Hong‐Ying, Sansom, Stephen N., Shikama‐Dorn, Noriko, Hafen, Katrin, Macaulay, Iain C., Deadman, Mary E., Ponting, Chris P., Takahama, Yousuke, Holländer, Georg A.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
Cellular Immune Response
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832341/
https://ncbi.nlm.nih.gov/pubmed/26694097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201545995
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