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Cancer Missense Mutations Alter Binding Properties of Proteins and Their Interaction Networks
Many studies have shown that missense mutations might play an important role in carcinogenesis. However, the extent to which cancer mutations might affect biomolecular interactions remains unclear. Here, we map glioblastoma missense mutations on the human protein interactome, model the structures of...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3682950/ https://ncbi.nlm.nih.gov/pubmed/23799087 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066273 |
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