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Phosphorylation in protein-protein binding: effect on stability and function

Post-translational modifications offer a dynamic way to regulate protein activity, subcellular localization and stability. Here we estimate the effect of phosphorylation on protein binding and function for different types of complexes from human proteome. We find that phosphorylation sites have a te...

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Hlavní autoři: Nishi, Hafumi, Hashimoto, Kosuke, Panchenko, Anna R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3240861/
https://ncbi.nlm.nih.gov/pubmed/22153503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2011.09.021
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