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Binding of Mn-deoxyribonucleoside triphosphates to the active site of the DNA polymerase of bacteriophage T7
Divalent metal ions are crucial as cofactors for a variety of intracellular enzymatic activities. Mg(2+), as an example, mediates binding of deoxyribonucleoside 5′-triphosphates followed by their hydrolysis in the active site of DNA polymerase. It is difficult to study the binding of Mg(2+) to an ac...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3676745/ https://ncbi.nlm.nih.gov/pubmed/23761703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1154/1.3583156 |
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