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DNA Recognition by the DNA Primase of Bacteriophage T7: A Structure#Function Study of the Zinc-Binding Domain DNA Recognition by the DNA Primase of Bacteriophage T7: A Structure–Function Study of the Zinc-Binding Domain

Synthesis of oligoribonucleotide primers for lagging-strand DNA synthesis in the DNA replication system of bacteriophage T7 is catalyzed by the primase domain of the gene 4 helicase-primase. The primase consists of a zinc-binding domain (ZBD) and an RNA polymerase (RPD) domain. The ZBD is responsibl...

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Detalhes bibliográficos
Main Authors: Akabayov, Barak, Lee, Seung-Joo, Akabayov, Sabine R., Rekhi, Sandeep, Zhu, Bin, Richardson, Charles C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880633/
https://ncbi.nlm.nih.gov/pubmed/19206208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi802123t
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