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Zinc-binding Domain of the Bacteriophage T7 DNA Primase Modulates Binding to the DNA Template

The zinc-binding domain (ZBD) of prokaryotic DNA primases has been postulated to be crucial for recognition of specific sequences in the single-stranded DNA template. To determine the molecular basis for this role in recognition, we carried out homolog-scanning mutagenesis of the zinc-binding domain...

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Detalles Bibliográficos
Main Authors: Lee, Seung-Joo, Zhu, Bin, Akabayov, Barak, Richardson, Charles C.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493944/
https://ncbi.nlm.nih.gov/pubmed/23024359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.414151
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