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Mechanism of sequence-specific template binding by the DNA primase of bacteriophage T7

DNA primases catalyze the synthesis of the oligoribonucleotides required for the initiation of lagging strand DNA synthesis. Biochemical studies have elucidated the mechanism for the sequence-specific synthesis of primers. However, the physical interactions of the primase with the DNA template to ex...

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Autores principales: Lee, Seung-Joo, Zhu, Bin, Hamdan, Samir M., Richardson, Charles C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910064/
https://ncbi.nlm.nih.gov/pubmed/20350931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq205
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