Neurological characterization of mice deficient in GSK3α highlight pleiotropic physiological functions in cognition and pathological activity as Tau kinase

BACKGROUND: GSK3β is involved in a wide range of physiological functions, and is presumed to act in the pathogenesis of neurological diseases, from bipolar disorder to Alzheimer’s disease (AD). In contrast, the GSK3α isozyme remained largely ignored with respect to both aspects. RESULTS: We generate...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Maurin, Hervé, Lechat, Benoit, Dewachter, Ilse, Ris, Laurence, Louis, Justin V, Borghgraef, Peter, Devijver, Herman, Jaworski, Tomasz, Van Leuven, Fred
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3671145/
https://ncbi.nlm.nih.gov/pubmed/23705847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-6-27
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados