Neurological characterization of mice deficient in GSK3α highlight pleiotropic physiological functions in cognition and pathological activity as Tau kinase

BACKGROUND: GSK3β is involved in a wide range of physiological functions, and is presumed to act in the pathogenesis of neurological diseases, from bipolar disorder to Alzheimer’s disease (AD). In contrast, the GSK3α isozyme remained largely ignored with respect to both aspects. RESULTS: We generate...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Maurin, Hervé, Lechat, Benoit, Dewachter, Ilse, Ris, Laurence, Louis, Justin V, Borghgraef, Peter, Devijver, Herman, Jaworski, Tomasz, Van Leuven, Fred
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3671145/
https://ncbi.nlm.nih.gov/pubmed/23705847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-6-27
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi