Genetic and Phenotypic Characterization of Manufacturing Seeds for a Tetravalent Dengue Vaccine (DENVax)

BACKGROUND: We have developed a manufacturing strategy that can improve the safety and genetic stability of recombinant live-attenuated chimeric dengue vaccine (DENVax) viruses. These viruses, containing the pre-membrane (prM) and envelope (E) genes of dengue serotypes 1–4 in the replicative backgro...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Huang, Claire Y.-H., Kinney, Richard M., Livengood, Jill A., Bolling, Bethany, Arguello, John J., Luy, Betty E., Silengo, Shawn J., Boroughs, Karen L., Stovall, Janae L., Kalanidhi, Akundi P., Brault, Aaron C., Osorio, Jorge E., Stinchcomb, Dan T.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2013
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667780/
https://ncbi.nlm.nih.gov/pubmed/23738026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002243
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