Immunogenicity and efficacy of chimeric dengue vaccine (DENVax) formulations in interferon-deficient AG129 mice

Formulations of chimeric dengue vaccine (DENVax) viruses containing the pre-membrane (prM) and envelope (E) genes of serotypes 1–4 expressed in the context of the attenuated DENV-2 PDK-53 genome were tested for safety, immunogenicity and efficacy in interferon receptor knock-out mice (AG129). Monova...

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Vydáno v:Vaccine
Hlavní autoři: Brewoo, Joseph N., Kinney, Richard M., Powell, Tim D., Arguello, John J., Silengo, Shawn J., Partidos, Charalambos D., Huang, Claire Y.-H., Stinchcomb, Dan T., Osorio, Jorge E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4592107/
https://ncbi.nlm.nih.gov/pubmed/22178727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2011.11.072
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