Efficacy of a Tetravalent Chimeric Dengue Vaccine (DENVax) in Cynomolgus Macaques

Three tetravalent formulations of chimeric dengue (DENVax) viruses containing the pre-membrane and envelope genes of serotypes 1–4 expressed by the attenuated DENV-2 PDK-53 genome were tested for safety, immunogenicity, and efficacy in cynomolgus macaques (Macaca fascicularis). Subcutaneous injectio...

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Bibliografiska uppgifter
Huvudupphovsmän: Osorio, Jorge E., Brewoo, Joseph N., Silengo, Shawn J., Arguello, John, Moldovan, Ioana R., Tary-Lehmann, Magdalena, Powell, Tim D., Livengood, Jill A., Kinney, Richard M., Huang, Claire Y.-H., Stinchcomb, Dan T.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society of Tropical Medicine and Hygiene 2011
Ämnen:
Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110349/
https://ncbi.nlm.nih.gov/pubmed/21633037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.2011.10-0592
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