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Safety and immunogenicity of a recombinant live attenuated tetravalent dengue vaccine (DENVax) in flavivirus-naive healthy adults in Colombia: a randomised, placebo-controlled, phase 1 study

BACKGROUND: Dengue virus is the most serious mosquito-borne viral threat to public health and no vaccines or antiviral therapies are approved for dengue fever. The tetravalent DENVax vaccine contains a molecularly characterised live attenuated dengue serotype-2 virus (DENVax-2) and three recombinant...

詳細記述

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書誌詳細
出版年:Lancet Infect Dis
主要な著者: Osorio, Jorge E, Velez, Ivan D, Thomson, Cynthia, Lopez, Liliana, Jimenez, Alejandra, Haller, Aurelia A, Silengo, Shawn, Scott, Jaclyn, Boroughs, Karen L, Stovall, Janae L, Luy, Betty E, Arguello, John, Beatty, Mark E, Santangelo, Joseph, Gordon, Gilad S, Huang, Claire Y-H, Stinchcomb, Dan T
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648257/
https://ncbi.nlm.nih.gov/pubmed/25087476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1473-3099(14)70811-4
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