Allosteric integrase inhibitor potency is determined through the inhibition of HIV-1 particle maturation

Integration is essential for HIV-1 replication, and the viral integrase (IN) protein is an important therapeutic target. Allosteric IN inhibitors (ALLINIs) that engage the IN dimer interface at the binding site for the host protein lens epithelium-derived growth factor (LEDGF)/transcriptional coacti...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Jurado, Kellie A., Wang, Hao, Slaughter, Alison, Feng, Lei, Kessl, Jacques J., Koh, Yasuhiro, Wang, Weifeng, Ballandras-Colas, Allison, Patel, Pratiq A., Fuchs, James R., Kvaratskhelia, Mamuka, Engelman, Alan
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2013
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666754/
https://ncbi.nlm.nih.gov/pubmed/23610442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1300703110
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars