A Mutation in EGF Repeat-8 of Notch Discriminates Between Serrate/Jagged and Delta Family Ligands

Notch signaling affects many developmental and cellular processes and has been implicated in congenital disorders, stroke, and numerous cancers. The Notch receptor binds its ligands Delta and Serrate and is able to discriminate between them in different contexts. However, the specific domains in Not...

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محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Yamamoto, Shinya, Charng, Wu-Lin, Rana, Nadia A., Kakuda, Shinako, Jaiswal, Manish, Bayat, Vafa, Xiong, Bo, Zhang, Ke, Sandoval, Hector, David, Gabriela, Wang, Hao, Haltiwanger, Robert S., Bellen, Hugo J.
التنسيق: Artigo
اللغة:Inglês
منشور في: 2012
الموضوعات:
Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663443/
https://ncbi.nlm.nih.gov/pubmed/23197537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1228745
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