A Mutation in EGF Repeat-8 of Notch Discriminates Between Serrate/Jagged and Delta Family Ligands

Notch signaling affects many developmental and cellular processes and has been implicated in congenital disorders, stroke, and numerous cancers. The Notch receptor binds its ligands Delta and Serrate and is able to discriminate between them in different contexts. However, the specific domains in Not...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Yamamoto, Shinya, Charng, Wu-Lin, Rana, Nadia A., Kakuda, Shinako, Jaiswal, Manish, Bayat, Vafa, Xiong, Bo, Zhang, Ke, Sandoval, Hector, David, Gabriela, Wang, Hao, Haltiwanger, Robert S., Bellen, Hugo J.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663443/
https://ncbi.nlm.nih.gov/pubmed/23197537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1228745
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires