Drosophila Tempura, a Novel Protein Prenyltransferase α Subunit, Regulates Notch Signaling Via Rab1 and Rab11

Vesicular trafficking plays a key role in tuning the activity of Notch signaling. Here, we describe a novel and conserved Rab geranylgeranyltransferase (RabGGT)-α–like subunit that is required for Notch signaling-mediated lateral inhibition and cell fate determination of external sensory organs. Thi...

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Autores principales: Charng, Wu-Lin, Yamamoto, Shinya, Jaiswal, Manish, Bayat, Vafa, Xiong, Bo, Zhang, Ke, Sandoval, Hector, David, Gabriela, Gibbs, Stephen, Lu, Hsiang-Chih, Chen, Kuchuan, Giagtzoglou, Nikos, Bellen, Hugo J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904817/
https://ncbi.nlm.nih.gov/pubmed/24492843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001777
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