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Canonical Notch ligands and Fringes have distinct effects on NOTCH1 and NOTCH2
Notch signaling is a cellular pathway regulating cell-fate determination and adult tissue homeostasis. Little is known about how canonical Notch ligands or Fringe enzymes differentially affect NOTCH1 and NOTCH2. Using cell-based Notch signaling and ligand-binding assays, we evaluated differences in...
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| Опубликовано в: : | J Biol Chem |
|---|---|
| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7586220/ https://ncbi.nlm.nih.gov/pubmed/32820046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014407 |
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