O-Glucose Trisaccharide Is Present at High but Variable Stoichiometry at Multiple Sites on Mouse Notch1

Notch activity is regulated by both O-fucosylation and O-glucosylation, and Notch receptors contain multiple predicted sites for both. Here we examine the occupancy of the predicted O-glucose sites on mouse Notch1 (mN1) using the consensus sequence C(1)XSXPC(2). We show that all of the predicted sit...

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Bibliographische Detailangaben
Hauptverfasser: Rana, Nadia A., Nita-Lazar, Aleksandra, Takeuchi, Hideyuki, Kakuda, Shinako, Luther, Kelvin B., Haltiwanger, Robert S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Glycobiology and Extracellular Matrices
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173066/
https://ncbi.nlm.nih.gov/pubmed/21757702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.268243
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