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Apoptosome structure, assembly and procaspase activation

Apaf-1 like molecules assemble into a ring-like platform known as the apoptosome. This cell death platform then activates procaspases in the intrinsic cell death pathway. In this review, crystal structures of Apaf-1 monomers and CED-4 dimers have been combined with apoptosome structures, to provide...

詳細記述

保存先:
書誌詳細
主要な著者: Yuan, Shujun, Akey, Christopher W.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3644875/
https://ncbi.nlm.nih.gov/pubmed/23561633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2013.02.024
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