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A near atomic structure of the active human apoptosome
In response to cell death signals, an active apoptosome is assembled from Apaf-1 and procaspase-9 (pc-9). Here we report a near atomic structure of the active human apoptosome determined by cryo-electron microscopy. The resulting model gives insights into cytochrome c binding, nucleotide exchange an...
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| I publikationen: | eLife |
|---|---|
| Huvudupphovsmän: | , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
eLife Sciences Publications, Ltd
2016
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5050015/ https://ncbi.nlm.nih.gov/pubmed/27697150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.17755 |
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