Satb1 regulates hematopoietic stem cell self-renewal by promoting quiescence and repressing differentiation commitment

How hematopoietic stem cells coordinate the regulation of opposing cellular mechanisms like self-renewal and differentiation commitment remains unclear. Here, we identified the transcription factor and chromatin remodeler Satb1 as a critical regulator of the hematopoietic stem cell (HSC) fate. HSCs...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Will, Britta, Vogler, Thomas O., Bartholdy, Boris, Garrett-Bakelman, Francine, Mayer, Jillian, Barreyro, Laura, Pandolfi, Ashley, Todorova, Tihomira I., Okoye-Okafor, Ujunwa C., Stanley, Robert F., Bhagat, Tushar D., Verma, Amit, Figueroa, Maria E., Melnick, Ari, Roth, Michael, Steidl, Ulrich
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633104/
https://ncbi.nlm.nih.gov/pubmed/23563689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2572
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg