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Glioblastoma Resistance to Anti-VEGF Therapy: Has the Challenge Been MET?

In glioblastoma cells the receptor tyrosine kinase c-Met is upregulated in response to Bevacizumab and plays an important role in promoting invasion and tumor recurrence. These data support novel links between VEGF-A and HGF and suggest that c-Met and its signaling effectors may be effective targets...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijä: McCarty, Joseph H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3618531/
https://ncbi.nlm.nih.gov/pubmed/23403631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-0051
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