Neuropilin-1 modulates TGFβ signaling to drive glioblastoma growth and recurrence after anti-angiogenic therapy

Glioblastoma (GBM) is a rapidly progressive brain cancer that exploits the neural microenvironment, and particularly blood vessels, for selective growth and survival. Anti-angiogenic agents such as the vascular endothelial growth factor-A (VEGF-A) blocking antibody bevacizumab yield short-term benef...

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Udgivet i:PLoS One
Main Authors: Kwiatkowski, Sam C., Guerrero, Paola A., Hirota, Shinya, Chen, Zhihua, Morales, John E., Aghi, Manish, McCarty, Joseph H.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5609745/
https://ncbi.nlm.nih.gov/pubmed/28938007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0185065
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