Neuropilin 1 balances β8 integrin-activated TGFβ signaling to control sprouting angiogenesis in the brain

Angiogenesis in the developing central nervous system (CNS) is regulated by neuroepithelial cells, although the genes and pathways that couple these cells to blood vessels remain largely uncharacterized. Here, we have used biochemical, cell biological and molecular genetic approaches to demonstrate...

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Detalles Bibliográficos
Publicado en:Development
Main Authors: Hirota, Shinya, Clements, Thomas P., Tang, Leung K., Morales, John E., Lee, Hye Shin, Oh, S. Paul, Rivera, Gonzalo M., Wagner, Daniel S., McCarty, Joseph H.
Formato: Artigo
Idioma:Inglês
Publicado: The Company of Biologists 2015
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4689212/
https://ncbi.nlm.nih.gov/pubmed/26586223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.113746
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