αvβ3 Integrin Limits the Contribution of Neuropilin-1 to Vascular Endothelial Growth Factor-induced Angiogenesis

Both vascular endothelial growth factor receptors (VEGFR) and integrins are major regulators of VEGF-induced angiogenesis. Previous work has shown that β3 integrin can regulate negatively VEGFR2 expression. Here we show that β3 integrin can regulate negatively VEGF-mediated angiogenesis by limiting...

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Главные авторы: Robinson, Stephen D., Reynolds, Louise E., Kostourou, Vassiliki, Reynolds, Andrew R., da Silva, Rita Graça, Tavora, Bernardo, Baker, Marianne, Marshall, John F., Hodivala-Dilke, Kairbaan M.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2009
Предметы:
Molecular Basis of Cell and Developmental Biology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797167/
https://ncbi.nlm.nih.gov/pubmed/19837659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.030700
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