Glioblastoma stem cells exploit the αvβ8 integrin-TGFβ1 signaling axis to drive tumor initiation and progression

Glioblastoma (GBM) is a primary brain cancer that contains populations of stem-like cancer cells (GSCs) that home to specialized perivascular niches. GSC interactions with their niche influence self-renewal, differentiation and drug resistance, although the pathways underlying these events remain la...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Guerrero, PA, Tchaicha, JH, Chen, Z, Morales, JE, McCarty, N, Wang, Q, Sulman, EP, Fuller, G, Lang, FF, Rao, G, McCarty, JH
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5882487/
https://ncbi.nlm.nih.gov/pubmed/28783169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2017.248
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