αvβ8 integrin interacts with RhoGDI1 to regulate Rac1 and Cdc42 activation and drive glioblastoma cell invasion

The malignant brain cancer glioblastoma multiforme (GBM) displays invasive growth behaviors that are regulated by extracellular cues within the neural microenvironment. The adhesion and signaling pathways that drive GBM cell invasion remain largely uncharacterized. Here we use human GBM cell lines,...

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Main Authors: Reyes, Steve B., Narayanan, Anjana S., Lee, Hye Shin, Tchaicha, Jeremy H., Aldape, Kenneth D., Lang, Frederick F., Tolias, Kimberly F., McCarty, Joseph H.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Cell Biology 2013
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3571870/
https://ncbi.nlm.nih.gov/pubmed/23283986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-07-0521
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