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Disease-causing mutations of RhoGDIα induce Rac1 hyperactivation in podocytes
Nephrotic syndrome (NS) describes a group of kidney disorders in which there is injury to podocyte cells, specialized cells within the kidney's glomerular filtration barrier, allowing proteins to leak into the urine. Three mutations in ARHGDIA, which encodes Rho GDP dissociation inhibitor α (GD...
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| 出版年: | Small GTPases |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Taylor & Francis
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4905261/ https://ncbi.nlm.nih.gov/pubmed/26726844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2015.1113353 |
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