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ARHGEF7 (β-PIX) Is Required for the Maintenance of Podocyte Architecture and Glomerular Function

BACKGROUND: Previous studies showed that Cdc42, a member of the prototypical Rho family of small GTPases and a regulator of the actin cytoskeleton, is critical for the normal development and health of podocytes. However, upstream regulatory mechanisms for Cdc42 activity in podocytes are largely unkn...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Am Soc Nephrol
Hauptverfasser: Matsuda, Jun, Maier, Mirela, Aoudjit, Lamine, Baldwin, Cindy, Takano, Tomoko
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Nephrology 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7217415/
https://ncbi.nlm.nih.gov/pubmed/32188698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2019090982
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