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Activation of RhoA in Podocytes Induces Focal Segmental Glomerulosclerosis

Proper organization of the actin cytoskeleton is essential for the normal structure and function of podocytes. RhoA modulates actin dynamics but its role in podocyte biology is controversial. Here, we generated transgenic mice that express a constitutively active form of RhoA in a podocyte-specific...

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Detalhes bibliográficos
Main Authors: Zhu, Lei, Jiang, Ruihua, Aoudjit, Lamine, Jones, Nina, Takano, Tomoko
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171934/
https://ncbi.nlm.nih.gov/pubmed/21804090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010111146
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