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Activation of RhoA in Podocytes Induces Focal Segmental Glomerulosclerosis
Proper organization of the actin cytoskeleton is essential for the normal structure and function of podocytes. RhoA modulates actin dynamics but its role in podocyte biology is controversial. Here, we generated transgenic mice that express a constitutively active form of RhoA in a podocyte-specific...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Nephrology
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3171934/ https://ncbi.nlm.nih.gov/pubmed/21804090 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010111146 |
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