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Podocyte Protein, Nephrin, Is a Substrate of Protein Tyrosine Phosphatase 1B

Glomerular podocytes are critical for the barrier function of the glomerulus in the kidney and their dysfunction causes protein leakage into the urine (proteinuria). Nephrin is a key podocyte protein, which regulates the actin cytoskeleton via tyrosine phosphorylation of its cytoplasmic domain. Here...

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Detalhes bibliográficos
Main Authors: Aoudjit, Lamine, Jiang, Ruihua, Lee, Tae Hoon, New, Laura A., Jones, Nina, Takano, Tomoko
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195428/
https://ncbi.nlm.nih.gov/pubmed/22013520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/376543
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