Nephrin Tyrosine Phosphorylation Is Required to Stabilize and Restore Podocyte Foot Process Architecture

Podocytes are specialized epithelial cells of the kidney blood filtration barrier that contribute to permselectivity via a series of interdigitating actin–rich foot processes. Positioned between adjacent projections is a unique cell junction known as the slit diaphragm, which is physically connected...

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Bibliographische Detailangaben
Veröffentlicht in:J Am Soc Nephrol
Hauptverfasser: New, Laura A., Martin, Claire E., Scott, Rizaldy P., Platt, Mathew J., Keyvani Chahi, Ava, Stringer, Colin D., Lu, Peihua, Samborska, Bozena, Eremina, Vera, Takano, Tomoko, Simpson, Jeremy A., Quaggin, Susan E., Jones, Nina
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Nephrology 2016
Schlagworte:
Basic Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4978059/
https://ncbi.nlm.nih.gov/pubmed/26802179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015091048
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