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The Role of Trio, a Rho Guanine Nucleotide Exchange Factor, in Glomerular Podocytes

Nephrotic syndrome is a kidney disease featured by heavy proteinuria. It is caused by injury to the specialized epithelial cells called “podocytes” within the filtration unit of the kidney, glomerulus. Previous studies showed that hyperactivation of the RhoGTPase, Rac1, in podocytes causes podocyte...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Maier, Mirela, Baldwin, Cindy, Aoudjit, Lamine, Takano, Tomoko
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5855701/
https://ncbi.nlm.nih.gov/pubmed/29415466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19020479
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