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The Role of Trio, a Rho Guanine Nucleotide Exchange Factor, in Glomerular Podocytes

Nephrotic syndrome is a kidney disease featured by heavy proteinuria. It is caused by injury to the specialized epithelial cells called “podocytes” within the filtration unit of the kidney, glomerulus. Previous studies showed that hyperactivation of the RhoGTPase, Rac1, in podocytes causes podocyte...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Maier, Mirela, Baldwin, Cindy, Aoudjit, Lamine, Takano, Tomoko
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5855701/
https://ncbi.nlm.nih.gov/pubmed/29415466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19020479
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