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The Role of Trio, a Rho Guanine Nucleotide Exchange Factor, in Glomerular Podocytes

Nephrotic syndrome is a kidney disease featured by heavy proteinuria. It is caused by injury to the specialized epithelial cells called “podocytes” within the filtration unit of the kidney, glomerulus. Previous studies showed that hyperactivation of the RhoGTPase, Rac1, in podocytes causes podocyte...

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Publicat a:Int J Mol Sci
Autors principals: Maier, Mirela, Baldwin, Cindy, Aoudjit, Lamine, Takano, Tomoko
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5855701/
https://ncbi.nlm.nih.gov/pubmed/29415466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19020479
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