ANGI-17. GLIOBLASTOMA STEM CELLS EXPLOIT THE ALPHAVBETA8 INTEGRIN-TGFBETA SIGNALING AXIS TO DRIVE TUMOR INITIATION AND PROGRESSION

Glioblastoma (GBM) is a primary brain cancer that contains populations of stem-like cancer cells (GSCs) that home to specialized perivascular niches comprised of vascular endothelial cells, pericytes and extracellular matrix (ECM)-rich basement membranes. Interactions with their niche influence GSC...

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Publicat a:Neuro Oncol
Autors principals: McCarty, Joseph, Sulman, Erik, Rao, Ganesh, Wang, Qianghu, Lang, Fred, Guerrero, Paola
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692497/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.095
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